Phosphodiesterases as Drug Targets (Handbook of Experimental Pharmacology 204)

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Management number 233410998 Release Date 2026/06/27 List Price US$83.13 Model Number 233410998
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Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors. Read more

ASIN B00F773MZQ
XRay Not Enabled
ISBN13 978-3642179693
Edition 2011th
Language English
File size 6.2 MB
Page Flip Enabled
Publisher Springer
Word Wise Not Enabled
Print length 538 pages
Accessibility Learn more
Part of series Handbook of Experimental Pharmacology
Publication date June 21, 2011
Enhanced typesetting Enabled

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